1. Definition of Late and Complicated Lesions Late lesions of atherosclerosis refer to fully developed fibrous (atheromatous) plaques These lesions arise from: Progressive enlargement of fatty streaks Recruitment of smooth muscle cells Accumulation of extracellular lipid Deposition of fibrous connective …
1. Definition of Early Lesion (Fatty Streak) The early lesion of atherosclerosis is known as the fatty streak It represents the earliest morphologically recognizable stage in the development of atherosclerosis Fatty streaks consist primarily of: Lipid-laden foam cells Located within …
1. Definition Atherosclerosis is a chronic, progressive, multifactorial disease of arteries, characterized by the formation of atheromatous plaques within the intima of large and medium-sized elastic and muscular arteries. These plaques are composed of: Lipids (cholesterol and cholesterol esters) Inflammatory …